MHC Class II (LGII-612.14) Mouse mAb 68258S from Cell Signaling Technology

Product Specs
ItemMHC Class II (LGII-612.14) Mouse mAb
CompanyCell Signaling Technology
Price Pricing Info Supplier Page View Company Product Page
Catalog Number68258S
Quantity100 µl
ApplicationsW, IP, IHC-Bond, IHC-P, FC-L
ReactivityH
TargetHLA-DRB1;HLA-DPB1
HostMouse
NCBI Full Gene Namemajor histocompatibility complex, class II, DP beta 1, major histocompatibility complex, class II, DR beta 1
NCBI Gene AliasesHLA-DRB, HLA-DP, SS1, HLA-DPB, HLA-DR1B, DPB1, HLA-DP1B, DRB1
ClonalityMonoclonal
Research AreaImmunology and Inflammation
Molecular Weight25-35, 50-65

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Cell Signaling Technology

3 Trask Lane

Danvers, Massachusetts 01923

United States

Phone: 877-616-CELL
Phone: 978-867-2388
Fax: 866-432-6112
Fax: 978-867-2488

Company Profile

Website: http://www.cellsignal.com/

Website: Technical Support

(1) PD-1 blockade in combination with dasatinib potentiates induction of anti-acute lymphocytic leukemia immunityJournal for ImmunoTherapy of CancerOctober 4, 2023Paul Koller, Natalia Baran, Karine Harutyunyan, Antonio Cavazos, Saradhi Mallampati, Renee L Chin, Zhou Jiang, Xian Sun, Heng-Huan Lee, Jennifer L Hsu, et al.Waltham, Massachusetts, USA). Antibodies included CIITA (Cat. 3793) and MHC Class II (LGII-612.14; Cat. 68258) from Cell Signaling (Danvers, Massachusetts, USA), and alpha-tubulin (B-5-1-2; Cat. T5168) from Sigma-Aldrich

(2) Cancer cell plasticity and MHC-II–mediated immune tolerance promote breast cancer metastasis to lymph nodesJournal of Experimental MedicineSeptember 4, 2023Pin-Ji Lei, Ethel R. Pereira, Patrik Andersson, Zohreh Amoozgar, Jan Willem Van Wijnbergen, Meghan J. O’Melia, Hengbo Zhou, Sampurna Chatterjee, William W. Ho, Jessica M. Posada, et al.heat-induced epitope retrieval in citrate-based antigen retrieval solution. MHC-II (LGII-612.14, Cat: #68258S; CST) and Anti-human pan-Cytokeratin-Alexa647 (Cat: #628604; BioLegend) were used for the staining.

(3) (−)-Guaiol triggers immunogenic cell death and inhibits tumor growth in non-small cell lung cancerMolecular and Cellular BiochemistryJuly 1, 2023Xiaohui Yang, Junling Yang, Xiaoxia Gu, Yuhua Tao, Hongjuan Ji, Xian Miao, Shuijie Shen, Haiyang ZangCD8(ab209775), CD69(ab202909), CD86(ab234401), CD11c (ab219799) were all purchased from Abcam. MHC II (#68258) was purchased from Cell Signaling Technology. Vaccination assay C57BL/6 mice were randomly divided

(4) Interferon gamma mediates the reduction of adipose tissue regulatory T cells in human obesityNature communicationsSeptember 24, 2022Bradley D, Smith AJ, Blaszczak A, Shantaram D, Bergin SM, Jalilvand A, Wright V, Wyne KL, Dewal RS, Baer LA, et al.Cell Signaling Technology: anti-phospho-STAT1 (Y701) (1:1000, 9171), anti-STAT1 (1:1000, 9172), and anti- MHCII (1:3000, 68258), from Abcam: anti-HLA-DPB1 (1:5000, ab157210), and from Santa Cruz: anti-β-actin (1:5000, sc-47778). STAT1

(5) Genome-wide Screens Identify Lineage- and Tumor-Specific Genes Modulating MHC-I- and MHC-II-Restricted Immunosurveillance of Human LymphomasImmunityJanuary 12, 2021Dersh D, Phelan JD, Gumina ME, Wang B, Arbuckle JH, Holly J, Kishton RJ, Markowitz TE, Seedhom MO, Fridlyand N, et al.,Cell Signaling,"Clone D9P5H, Cat# 15106S" MHC-II (Western blot),Cell Signaling,"Clone LGII-612.14, Cat# 68258S" CIITA (Western blot),Santa Cruz,"Clone 7-1H, Cat# sc-13556" CIITA (immunoprecipitation),Cell Signaling,"rabbit

(6) Identification of tumor-associated macrophage subsets that are associated with breast cancer prognosisClinical and translational medicineDecember 1, 2020Strack E, Rolfe PA, Fink AF, Bankov K, Schmid T, Solbach C, Savai R, Sha W, Pradel L, Hartmann S, et al.(Atlas Antibodies, Bromma, Sweden, HPA000395, RRID:AB_1079405), anti‐MHCII (Cell Signaling, Danvers, MA, 68258S), anti‐pan‐cytokeratin (abcam, Cambridge, UK, ab7753, RRID:AB_306047), anti‐collagen I (abcam, Cambridge,

(7) Neuroendocrine subtypes of small cell lung cancer differ in terms of immune microenvironment and checkpoint molecule distributionMolecular OncologySeptember 1, 2020David Dora et al.using rabbit monoclonal antibody for IDO (#86630), CD45 (#13917), CD3 (#85061), CD8 (#8112), MHC II (#68258), PD‐L1 (13684S), and PVR (#81254) from Cell Signaling (Danvers, MA, USA) and diluted 1 : 200 with Cell

(8) BDNF reverses aging-related microglial activationJournal of neuroinflammationJuly 14, 2020Wu SY, Pan BS, Tsai SF, Chiang YT, Huang BM, Mo FE, Kuo YM.Osaka, Japan) for microglia, mouse anti-major histocompatibility complex (MHC) Class II (1:500, Cat. #: 68258S, Cell Signaling Technology, Danvers, MA, USA) for activated microglia, rabbit anti-tyrosine hydroxylase

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MHC Class II (LGII-612.14) Mouse mAb from Cell Signaling Technology

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Cell Signaling Technology

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MHC Class II (LGII-612.14) Mouse mAb from Cell Signaling Technology

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